Vaccination, Immunity and Breakthrough: Quantitative Effects in Individual Immune Responses Illustrated by a Simple Kinetic Model

The personal risks of infection, as well the conditions for achieving herd immunity, are strongly dependent on an individual’s response to infective agents one hand, and reactions vaccination other hand. main goal this work is illustrate importance quantitative individual effects disease risk in a simple way. applied model was able effects, cases different reactions, after exposition viruses or bacteria vaccines. based kinetic equations stimulation antibody production using concentrations agent, vaccine antibodies. It gave qualitative explanation differences breakthrough requirements concerning second, third further vaccinations, reconsidering efficiencies immune reaction.